CATHODE LUMINESCENCE OF NORMAL AND CANCEROUS CELLS

Abstract

A method was developed for determining the antioxidative effect in culture cells and cells prepared by means of the trypsinization of animal tissues, based on the dying out of luminescence which accompanies the free radical processes at the cathode during the passage of direct current with a density of 200 ma/sq cm through a suspension of cells. It was established that cancerous cells, prepared by means of trypsinization of cancer of the stomach and cancer of the mammary glands, and also culture cells of a cancerous origin: Hela, Hep-2, CaPa, CaMa -- lose luminescence more intensively than normal cells, prepared by trypsinization of monkey kidneys, lungs of a 3--5 month old human embryo, and 9-day chick embryos. Based on their antioxidative effect, the culture cells of non-cancerous origin (sots, strain 580, cells from an upper limb of a 3-month old human embryo) approximate those of cancerous cells (Hela, Hep-2, and others).

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Document Details

Document Type
Technical Report
Publication Date
Aug 12, 1965
Accession Number
AD0641750

Entities

People

  • B. N. Tarusov
  • V. S. Pyatenko

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Amino Acids
  • Antioxidants
  • Aromatic Amino Acids
  • Cells
  • Direct Current
  • Electrolytic Cells
  • Emission
  • Free Radicals
  • Glands
  • Heart
  • Intensity
  • Luminescence
  • Mammary Glands
  • Russian Language
  • Saline Solution
  • Urogenital System

Readers

  • Immunology
  • Molecular Biology and Genetics
  • Virology (or Medical Virology).