COMPARATIVE STUDIES ON THE EFFECT OF ANTIBIOTICS AND GAMMA-GLOBULINE IN EXPERIMENTAL MELIOIDOSIS INFECTION

Abstract

Of the 5 examined antibiotics, the most pronounced therapeutical properties were found in levomycetin and biomycin which prevented death in 63.3 to 66.6% of animals infected with 200 mln. of microbes of virulent culture melioidosis causative agent. Treatment of experimental animals with gamma- globulin increased their survival twice as compared to the controls. These experiments are preliminary; nevertheless, their results show the expediency in the use of domestic antibiotics (native to their country) in emergency cases biomycin and levomycetin in combination with the gamma-globulin.

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Document Details

Document Type
Technical Report
Publication Date
May 03, 1960
Accession Number
AD0642047

Entities

People

  • A. P. Debiatova
  • E. D. Shkurko
  • L. E. Khudanov
  • V. I. Lukianova
  • Z. F. Padalko

Tags

Communities of Interest

  • Counter WMD

DTIC Thesaurus Topics

  • Animals
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Diseases And Disorders
  • Gamma Globulin
  • Globulins
  • Infection
  • Laboratory Animals
  • Melioidosis
  • Survival
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Aviation Safety Risk Assessment.
  • Infectious Disease/Epidemiology
  • Oncology (Cancer Research).