DYNAMICS OF MULTIPLICATION OF THE VEE VIRUS IN TISSUE CULTURE CELLS

Abstract

The virus of Venezuelan equine encephalomyelitis is capable of agglutinating goose erythrocytes at a pH of 5.8--6.0. The 'threshold of infectivity' which is necessary for the exposure of VEE hemagglutinins comprises 4.6--5.7 lg TCD50 1,300,000--2,600,000 plaque forming units). The reaction of hemadsorption makes it possible to expose the multiplication of VEE in 6--9 hours following infection of a sensitive culture. The RGA and the reaction of hemadsorption may be used for determining the dynamics of multiplication of VEE and the early diagnosis of this virus. A prolonged liberation of virus particles into the surrounding medium is characteristic for VEE.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1965
Accession Number
AD0642077

Entities

People

  • D. I. Ivanovskago
  • F. E. Ershov
  • V. A. Vagzhanova

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arbovirus Infections
  • Biological Laboratories
  • Blood
  • Cells
  • Dynamics
  • Infection
  • Infectious Diseases
  • Microbiology
  • Tissue Culture
  • Tissue Culture Cells
  • Vaccines
  • Venezuelan Equine Encephalomyelitis
  • Virion
  • Virology
  • Viruses
  • Wound Infections
  • Yellow Fever

Fields of Study

  • Biology

Readers

  • Immunology
  • Virology (or Medical Virology).