REGULATION OF RNA SYNTHESIS.
Abstract
Measurements of rRNA and tRNA content of E.Coli Ki2 cells have been made in the following situations: (a) exponential growth in media giving rise to different growth rates; (b) shift up from mineral to rich (in amino acids) medium; (c) starvation of a relaxed mutant; (d) chloramphenicol treatment; (e) shift down from rich to mineral medium. The conclusions are that (1) the stringent control, which acts during an amino acid starvation, works on both rRNA and tRNA; and (2) the control mechanism involved in the regulation of RNA content versus chemical environment works differentially on both species. A mutant with a peculiar behavior during a shift up experiment is described, and a new relaxed mutation is described. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 30, 1966
- Accession Number
- AD0642385
Entities
People
- R. Lavalle