VIRUS GROWTH - GENE REPRESSION HYPOTHESIS OF RADIATION PROTECTION BY AUXIN ANALOGUES.
Abstract
A working hypothesis is developed which postulates (1) that death from radiation sickness in mammals is to an appreciable extent the result of the activation of initially latent but potentially cytopathic viruses, and (2) that a radiation-protective auxin analogue blocks such activation by allosterically stabilizing an active form of an auxin-sensitive repressor of a viral gene. The phenomena of lysogeny and virogeny are used as models to develop this hypothesis. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1966
- Accession Number
- AD0644987
Entities
People
- David Norman
- Robert D. Schultz
Organizations
- Douglas