ABERRANT CORNEAL EPITHELIAL CELLS PRODUCED BY RUBY LASER IRRADIATION,

Abstract

Rat corneas were exposed to either 4 joules per sq cm or 8 joules per sq cm and were harvested at varying times following laser exposure. Corneal whole mounts were evaluated for changes in either the differential mitotic cell count or the mitotic index. Ruby laser radiation (6,943 A) produces aberrations in the corneal epithelium of the rat. At 8 joules per sq cm both interphase cells and cells in active mitosis were obviously altered. At 4 joules per sq cm aberrant corneal epithelial cells became apparent immediately after laser irradiation, and some were still present 30 days later. The mechanism by which laser radiation alters the cornea remains obscure. (Author)

Document Details

Document Type
Technical Report
Publication Date
Oct 31, 1966
Accession Number
AD0645452

Entities

People

  • Robert S Fisher
  • W. H. Parr

Tags

DTIC Thesaurus Topics

  • Cell Count
  • Cells
  • Electromagnetic Radiation
  • Epithelial Cells
  • Epithelium
  • Laser Safety
  • Lasers
  • Radiation
  • Ruby Lasers

Readers

  • Mathematics or Statistics
  • Molecular Biology and Genetics
  • Optical Physics and Photonics.

Technology Areas

  • Directed Energy
  • Directed Energy - Lasers