SOME STATISTICAL TREATMENTS COMPATIBLE WITH INDIVIDUAL ORGANISM METHODOLOGY.
Abstract
Consider experimental treatments with consequences so irreversible that baseline performance cannot be recovered. The conventional method of assessing the effects of such treatments by statistical means involves separate experimental and control groups. An alternative proposed here is to administer the experimental treatment to each subject, one subject at a time and in a random order; whenever any subject receives the experimental treatment, those subjects which have not yet received it receive a control treatment. This procedure permits results significant at the one-tailed .05 level to be obtained with four subjects; if a two-group procedure evaluated by means of the U test is used, a minimum of six subjects is needed for the same significance level. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 21, 1967
- Accession Number
- AD0646751
Entities
People
- Samuel H. Revusky
Organizations
- United States Army Medical Research Laboratory