DIFFERENTIATION BETWEEN PROTEOLYTIC AND TAME ESTEROLYTIC ACTIVITY IN CROTALUS ATROX VENOM.

Abstract

Although Crotalus atrox venom can hydrolyze proteins and arginine esters, these activities are not due to a trypsin-like enzyme. Proteolytic and esterolytic activities have been differentiated by specific inhibition by such compounds as PMSF, DFP, EDTA and 2-mercaptoethanol, and by actual resolution of the venom by DEAE-cellulose chromatography. Preliminary results suggest that the proteolytic activity in the venom may have a limited specificity and that this specificity is quite unlike that of trypsin and plasmin. (Author)

Document Details

Document Type
Technical Report
Publication Date
Dec 12, 1966
Accession Number
AD0647148

Entities

People

  • Donald E. Reed
  • Jesse D. Bobbitt

Organizations

  • United States Army Medical Research Laboratory

Tags

DTIC Thesaurus Topics

  • Analytical Chemistry Techniques
  • Biomolecules
  • Biopolymers
  • Carbohydrates
  • Cellulose
  • Chemical Compounds
  • Chromatography
  • Food
  • Inhibition
  • Macromolecules
  • Molecules

Fields of Study

  • Biology
  • Chemistry

Readers

  • Molecular and Cellular Biochemistry