CARDIOVASCULAR TRAUMA STUDY ON PERIPHERAL VESSELS,
Abstract
The project is concerned with cardio-vascular trauma study of peripheral vessels. For this investigation it was necessary to make an accurate and immediate recording of changes in blood volume, blood pressure and pulse rate in their actual units. An Offner type R polygraph was modified to incorporate new elements integrated for the purpose of printing these variables. A United Systems Digitex Voltmeter to perform the analog to digital conversion, a digital clock, and a printer were utilized with a multiplex (designed and built at the Medical Instrumentation Laboratory) to accomplish this digital printout. This modified unit allows for direct observation of the absolute values of the variables as they occur. This type of analog to digital printout system allows rapid programming of data for computer analysis. It was also necessary to develop a cardiovascular trauma apparatus which could perform reproducible and clean perforation of vessels from one preparation to the next. Thirty-one healthy coonhounds were studied under standardized conditions. Following blood volume measurements, a large peripheral vessel, artery or vein, was transected and the rate of blood loss continuously recorded, as well as blood pressure, heart rate and E.K.G. Data obtained was analyzed by B.M.R.L. Rate of blood loss was studied as a function of size and location of vessel (artery or vein) as well as fraction of original blood volume. Average blood loss at end of experiment (cessation of bleeding) was 47% of blood volume. Twenty-five animals were rapidly retransfused with plasmagel and modified fluid gelatin. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1967
- Accession Number
- AD0647344
Entities
People
- David V. Habif
Organizations
- Columbia University