FLUORESCENT ANTIBODIES FOR THE DETECTION OF RICKETTSIAE (REVIEW OF THE LITERATURE)
Abstract
The detection of rickettsiae in various materials and their identification are connected with a number of difficulties. For these purposes up until the present time it was possible to use only complex immunobiological and serological methods which took a long time to carry out. In some cases the establishment of the rickettsial nature of a causative agent was made more complex by the necessity of preparing antigen from the isolated microorganisms. In connection with this the interest and attention paid to the luminescent- serological method of investigation by investigators working in the field of rickettsioses is understandable. This method, combining a morphological and serological appraisal, makes it possible to judge concerning the nature of the causative agent or to observe it during the course of the development of the pathological process. The method turned out to be suitable for the serological investigations during rickettsial diseases with the purpose of exposing antibodies in the blood of the patients.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1965
- Accession Number
- AD0648071
Entities
People
- E. N. Levins
- M. Ya. Korn
- N. M. Balaeva
Organizations
- United States Army Biological Warfare Laboratories