EFFECT OF DRY CHICKEN EGG YOLK ON WHITE MOUSE SUSCEPTIBILITY TO PLAGUE,
Abstract
Tests of cortisone, novoembichine (nitrogen mustard), sodium glycocholate, and fresh chicken egg yolk as preparations to increase the susceptibility of white mice to the plague bacillus showed that fresh egg yolk is the most potent both in number of animals dying and in the length of life after inoculation. Egg yolk dried by the method of sublimation is just as effective as fresh egg yolk. The inoculation of even small doses of weakly virulent strains with dry egg yolk causes most animals to die, with cultures easily isolated from them. The use of dry egg yolk to increase the susceptibility of test animals (white mice) to plague is of value in improving the diagnosis of this infection in rodents under natural conditions. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1964
- Accession Number
- AD0648095
Entities
People
- L. A. Timofeeva
Organizations
- Aberystwyth University