CHANGES IN THE PHAGOCYTIC ACTIVITY OF LEUKOCYTES IN THE PROCESS OF IMMUNOGENESIS FOLLOWING ANTIPLAGUE VACCINATION

Abstract

During the first 12 days after subcutaneous injection to animals of the antiplague live vaccine the phagocytic number in leukocytes increases by 50- 100%, whereas the number of active leukocytes increases by 10-15%. Subsequently the phagocytic number slightly decreases but remains higher than in control animals. The percentage of active leukocytes increases on the 19-21st day after immunization by 20-25%. In the experiments with exudate in vivo the phagocytic number in immune animals is considerably higher than in the experiments with the blood in vitro. A completed phagocytic reaction is observed in white mice immunized with live antiplague vaccine EB, whereas in control (intact) mice there is no completed phagocytosis, as a rule.

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Document Details

Document Type
Technical Report
Publication Date
Jan 08, 1964
Accession Number
AD0648104

Entities

People

  • G. I. Borsuk

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abdomen
  • Adaptive Immunity
  • Animals
  • Antigens
  • Bacteria
  • Blood
  • Blood Cells
  • Cells
  • Immunity
  • Immunization
  • Infection
  • Leukocytes
  • Resistance
  • Rodents
  • Vaccination
  • Vaccines
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology

Technology Areas

  • Biotechnology