CAUSES UNDERLYING THE LOWERING OF THE NATURAL RESISTANCE OF IRRADIATED ANIMALS TO LIVE BRUCELLOSIS VACCINE
Abstract
An increase in the death of irradiated laboratory animals was observed following the administration of live or heat killed vaccine cultures of brucella, and also by the administration of the endotoxin which was extracted from them. The intensity of seeding of organs by the brucella vaccine strain was not intensified and its residual virulence was not increased. In the lowering of the resistance of irradiated animals to the vaccine strain, Br. abortus No 19-BA, a leading role resides in the increased sensitivity to the brucella endotoxin.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1966
- Accession Number
- AD0648115
Entities
People
- Z. V. Shevtsova
Organizations
- United States Army Biological Warfare Laboratories