THE EFFECT OF OXYGEN ON DOG PLASMA SULFHYDRYL GROUPS IN VITRO.

Abstract

A method is described in which biologic fluids are continuously exposed to a test atmosphere, and sampling is achieved without disruption of the atmosphere. Samples are withdrawn at intervals and analyzed for sulfhydryl content by amperometric titration with the rotating platinum electrode using AgNO3 as the titrant. Inasmuch as this project was undertaken to study the effect of oxygen on sulfhydryl-containing enzymes in vitro, the system was first evaluated using dog plasma as the source of protein. The decrease in dog plasma sulfhydryl content over a 4-hour exposure was: 9.3% for nitrogen, 24.7% for air, and 39.2% for oxygen. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1967
Accession Number
AD0648127

Entities

People

  • Methodius J. Bartek

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

DTIC Thesaurus Topics

  • Atmospheres
  • Electrodes
  • Elements
  • Intervals
  • Nitrogen
  • Platinum
  • Sampling
  • Titration

Readers

  • Analytical Chemistry
  • Cardiovascular Physiology
  • Molecular and Cellular Biochemistry