INCREASED RADIATION RESISTANCE OF MICE INJECTED WITH BEE VENOM ONE DAY PRIOR TO EXPOSURE

Abstract

Mice were injected with bee venom dissolved in a 0.90% NaCl solution. This injection was given either intraperitoneally or subcutaneously 24 hours before the mice were irradiated with X rays. It was found that, after exposure to a lethal dose of radiation (800 - 850 R) the venom-injected mice had a consistently higher number of survivals than the controls, and that the subcutaneously-injected mice had a higher number of survivals than the intraperitoneally-injected mice. The question as to whether this radioprotective effect of bee venom is due to its general stress-like effect, or to the action of a specific chemical component is discussed.

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Document Details

Document Type
Technical Report
Publication Date
Dec 20, 1966
Accession Number
AD0648139

Entities

People

  • Leonard J. Cole
  • William H. Shipman

Organizations

  • Naval Radiological Defense Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Bacterial Toxins
  • Biological Sciences
  • Body Weight
  • Complex Mixtures
  • Endocrine Glands
  • Ionizing Radiation
  • Laboratory Animals
  • Lethal Dosage
  • New York
  • Physiological Effects
  • Radiation
  • Radiation Protection
  • Radiation Resistance
  • Resistance
  • Sulfur Compounds
  • X Rays

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biology
  • Nuclear and Radiation Engineering.
  • Toxicology/Environmental Toxicology