CAPILLARY THROMBOSIS AS A CAUSE OF DEATH IN EXPERIMENTAL ANTHRAX
Abstract
The lungs of rats, rabbits, and guinea pigs that died of anthrax septicemia were studied by light and electron microscopy. In all three species, the clinical signs of respiratory failure that occurred during the terminal phase of the disease were associated with widespread pulmonary capillary thrombosis. The thrombi occurred in intact capillaries and were composed of platelets and fibrin. These results are compared with previous observations in rats given anthrax toxin and the significance of pulmonary capillary thrombosis as a factor in the cause of death in anthrax is discussed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 13, 1966
- Accession Number
- AD0650184
Entities
People
- Francis A. Beall
- Frederic G. Dalldorf
Organizations
- University of North Carolina at Chapel Hill