IMMUNIZATION OF MAN WITH THE LIVE M-44 Q-FEVER VACCINE

Abstract

In a test on humans (495 men) the weak reactogenicity of the live M- 44 vaccine in a dose of 0.0001 and its immunological effectiveness were established. A positive result in the complement fixation reaction was obtained in 82.3 plus or minus 4%, the average titer was 1:26.6. The vaccination of persons whose sera contained specific complement fixing antibodies prior to inoculation did not cause allergic reactions in them. Consequently the live M- 44 vaccine against Q-fever may be used for inoculation without a preliminary serological investigation.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1966
Accession Number
AD0651136

Entities

People

  • A. N. Sterkhova

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Antibodies
  • Biological Laboratories
  • Blood
  • Health
  • Health Services
  • Hygiene
  • Infectious Disease Transmission
  • Inoculation
  • Laboratory Animals
  • Medical Examination
  • Public Health
  • Q Fever
  • Ussr
  • Vaccination

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology

Technology Areas

  • Biotechnology