OBSERVATIONS ON THE VARIABILITY OF THE PLAGUE BACILLUS IN THE FLEAS. II. PASSAGE OF THE AVIRULENT SUBCULTURE 610-A THROUGH FLEAS AND PREGNANT GUINEA PIGS
Abstract
Results showed that the avirulent properties of the 610-A subculture, which remained the same following its passage through the organism of 'normal' susceptible animals, under other conditions (passage through the organism of pregnant guinea pigs or as a result of prolonged residence in the gastro- intestinal tract of active plague carriers -- the fleas X. cheopis and X. minax) may change to the side of a noticeable increase of virulence. The possibility of the transmission of the subculture under study from infected fleas during bloodsucking supplements the data obtained, which strongly sheds a certain light on the variability of the causative agent under natural conditions.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1966
- Accession Number
- AD0651196
Entities
People
- L. M. Osadchaya
- N. M. Khrusteselevskaya
- V. A. Bibikova
Organizations
- United States Army Biological Warfare Laboratories