FLUORESCENCE MICROSCOPY FOR THE IN VITRO STUDY OF THE INTRACELLULAR DIGESTION PROCESS IN PHAGOCYTIZED BACTERIA

Abstract

Fluorescence microscopy was used successfully for the in vitro study of the intracellular digestion of phagocytized bacteria. During fluorochroming with acridine orange it was possible to observe changes in the brightness and color of fluorescence of phagocytized bacteria. These changes were recorded (in a black-white image) with the help of a fluorescence cinemicrography technique. One of the possible reasons for changes in the brightness and color of fluorescence of phagocytized bacteria is the enzymatic destruction of high molecular biopolymers (proteins, nucleoproteins).

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1966
Accession Number
AD0651238

Entities

People

  • M. Ya. Korn

Tags

DTIC Thesaurus Topics

  • Acridines
  • Bacteria
  • Blood
  • Brightness
  • Cells
  • Digestive System Processes
  • Fluorescence
  • Ionizing Radiation
  • Leukocytes
  • Macrophages
  • Microbiology
  • Microorganisms
  • Microscopes
  • Microscopy
  • Molecules
  • Nucleic Acids
  • Rodents

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Molecular and Cellular Biochemistry