CORRELATION OF THE INDICES OF IMMUNOLOGICAL SHIFTS IN ANIMAL ORGANISMS UNDER THE INFLUENCE OF IMMUNIZATION WITH STAPHYLOCOCCUS AND DIPHTHERIA TOXOIDS, REPORT II,
Abstract
Intracutaneous and subcutaneous immunization with staphylococcus toxoid guaranteed similarly high indices in the intensity of the increase of antibodies (32 AU) and the degree of anti-infection protection (83.3% surviving animals). The results of calculating the dermonecrotic tests with staphylococcus cultures and toxin testified to the greater effectiveness of intracutaneous inoculations in comparison with subcutaneous. The intracutaneous administration of diphtheria toxoid caused an increase in the level of antibodies (an average of up to 15 AU), and an increase of anti-infection protection (57.1% surviving animals), and was accompanied by a sharp suppression of dermonecrotic reactions. The intracutaneous immunization of rabbits with diphtheria and staphylococcus toxoids reflected sharply on the intensity and duration of cutaneous reactions, caused by the administration of the corresponding antigens. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1966
- Accession Number
- AD0651239
Entities
People
- A. V. Lizgunova
Organizations
- United States Army Biological Warfare Laboratories