CONCERNING OXYGEN DEFICIENCY DURING EXPERIMENTAL PLAGUE INFECTION

Abstract

During experimental plague infection in guinea pigs, an oxygen deficiency was observed after one day. In the arterial and venous blood of guinea pigs infected with B. pestis the content of oxygen lowered significantly with the course of the experimental plague process. The oxygen capacity of the blood was reduced along with a simultaneous increase in the content of hemoglobin, which indicates a change in the biological properties of hemoglobin as an oxygen carrier. The oxygen deficiency which developed in guinea pigs during the process of plague infection cannot be confined to the framework of one type of hypoxia and includes elements of hypoxic, anemic and circulatory hypoxia.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1966
Accession Number
AD0652664

Entities

People

  • K. M. Mokhin

Organizations

  • United States Army Biological Warfare Laboratories

Tags

Communities of Interest

  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Animals
  • Blood
  • Blood Flow
  • Brain
  • Deficiencies
  • Diffusion
  • Glycogen
  • Heart
  • Infection
  • Lung
  • Materials
  • Microvessels
  • Nervous System
  • Rodents
  • Tissues
  • Tuberculosis
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Immunology