COMPARATIVE STUDY OF ALLERGIC REACTIONS IN MONKEYS TO P.P.D. AND KOCH'S OLD TUBERCULIN.

Abstract

P.P.D. possesses obvious advantages over Koch's old tuberculin relative to sensitivity after BCG vaccination. Monkeys show a 50% positive reactivity to P.P.D. and only 16% to Koch's old tuberculin. In lower monkeys, Koch's old tuberculin elicits no allergic reaction, through P.P.D. does. Using this fact, Burnet's hypothesis concerning allergy in lower monkeys was demonstrated to be untenable. Follow-up tuberculin reactivity tests conducted one year later indicated no essential deviation in further allergic reaction development in monkeys. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1967
Accession Number
AD0653947

Entities

People

  • M. A. Linnikova

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

DTIC Thesaurus Topics

  • Biological Therapy
  • Communicable Disease Control
  • Health
  • Health Care
  • Immune System Phenomena
  • Immunity
  • Immunization
  • Immunomodulation
  • Immunotherapy
  • Medical Specialties
  • Reactivities
  • Sensitivity
  • Vaccination

Fields of Study

  • Psychology

Readers

  • Immunology

Technology Areas

  • Biotechnology