EFFECT OF URICOSURIC DRUG ADMINISTRATION ON URIC ACID LEVELS IN UNSTIMULATED PAROTID FLUID.
Abstract
Parotid fluid was collected twice daily without exogenous stimulation from 6 healthy young adult males, both before and during a 5-day period of uricosuric drug dosage. A highly significant decrease in serum uric acid concentration was brought about by drug administration and a parallel decrease was found in parotid fluid uric acid concentration and uric acid secretion rate. The mean for serum uric acid decreased from 5.40 to 2.06 mg./100 ml. and parotid fluid uric acid concentration fell from 10.16 to 4.23 mg./100 ml. (morning samples) and 7.29 to 3.90 mg./100 ml. (afternoon samples). (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1967
- Accession Number
- AD0654290
Entities
People
- Howard H. Chauncey
- Ira L. Shannon
Organizations
- United States Air Force School of Aerospace Medicine