STUDIES ON THE SCREENING OF ANTIBIOTICS FOR ANTHELMINTIC USE.

Abstract

Although many kinds of anthelminthics are used for treatment of parasitic infections, most of them show relatively high toxic side-effects for patients. In addition, there are some kinds of parasitic infections for which special treatment has not yet been found. Therefore, development of antibiotics which are less toxic for patients and more effective against helminthic infections has been desired during a couple of decades. The purpose of the present investigation is to detect antibiotics which is effective against schistosome and nematode infections. Experiments were performed in dual purpose: to compare anti-schistosomal action of the antibiotic substances with that of some anti-schistosomal drugs currently used, and to evaluate possibility of using Nematospiroides dubius, trichostrongyle of mice, as a criterion of anti-nematode action of drugs. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1967
Accession Number
AD0655052

Entities

People

  • Toja Hata

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacterial Infections And Mycoses
  • Diseases And Disorders
  • Helminthiasis
  • Infection
  • Nematoda
  • Pharmacologic Actions
  • Side Effects
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Marine Ecological Systems Migration
  • Theoretical Analysis.