FEEDING THROUGH THE SKIN WITH DIMETHYL SULFOXIDE.
Abstract
The use of dimethyl sulfoxide (DMSO) to allow substances, including drugs, to pass through the skin had been reported in the literature. However, none of the studies pertained to the efficacy of using DMSO with nutrients. A seven-year-old Negro male dying of malnutrition, secondary to small bowel removal, was given several supplemental nutrients across the skin by the use of DMSO. A rise in blood glucose, serum carotene, urinary amino acids, and urinary Cobalt57B12, as well as a gain in weight after application of the nutrients to the skin, documented passage across the skin. The patient received 3,000 ml of 100 per cent DMSO during a seven-week period without evidence of toxicity. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1967
- Accession Number
- AD0656687
Entities
People
- Andrew M. Hegre Jr.
- Clement N. Rieffel Jr
- Robert E. Smith
Organizations
- Dartmouth College