THE EFFECT OF SOME PROTECTIVE SUBSTANCES ON THE PROCESS OF FREEZING AND THAWING OF CELLULAR ELEMENTS IN THE BLOOD.

Abstract

Damage to blood cells in blood taken with the usual glucose-citrate solution with out the addition of protective substances, occurs during the process of freezing and thawing, apparently, occurs essentially during the stage of thawing. Ethyl alcohol, used as a protective substance, in a complex glucose-citrate solution, protects to a certain degree, the blood cells during the process of freezing and thawing in spite of intensive re-crystallization, even at relatively low temperature. In the concentrated solution, containing two protective substances (ethyl alcohol and glycerine), the process of recrystallization is weak. At temperatures to -50C a considerable portion of the solution remains non-crystallized and fills up the canals between the crystals in which there are present some mobile cells. (Author)

Document Details

Document Type
Technical Report
Publication Date
Aug 11, 1967
Accession Number
AD0658850

Entities

People

  • G. A. Kozlov
  • V. I. Teodorovich

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Blood
  • Blood Cells
  • Cells
  • Critical Temperature
  • Crystallization
  • Crystals
  • Freezing
  • Glass Transition Temperature
  • Isothermal Processes
  • Low Temperature
  • Phase Transformations
  • Recrystallization
  • Transition Temperature

Fields of Study

  • Chemistry

Readers

  • Polymer Science and Engineering.
  • Systems Analysis and Design
  • Thermal Physics or Thermal Science.