PATHOPHYSIOLOGICAL STUDIES OF TEN POISONOUS SNAKE VENOMS.

Abstract

In an attempt to determine the exact physiological changes that follow the administration of a lethal dose of snake venom, the following studies were carried out: One thousand eight hundred and sixty-four mice and two hundred and forty-seven dogs were injected with varying doses of venom and changes in EEG, heart rate, EKG, respiration and blood pressure followed until death. Results indicate that on a mg/kg basis, the lethal dose of venom for the dog is significantly less than that for the mouse and that the mechanism of death for most venoms is respiratory in nature. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1966
Accession Number
AD0658986

Entities

People

  • Henry P. Ciuchta
  • James A. Vick
  • James H. Manthei
  • Richard Degraff

Tags

DTIC Thesaurus Topics

  • Cardiovascular Physiological Phenomena
  • Heart Rate
  • Lethal Dosage
  • Respiration

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Educational Psychology
  • Toxicology/Environmental Toxicology