DEVELOPMENT OF SKELETAL MUSCLE.
Abstract
Primary myotubes are believed to originate from miotimic myoblasts; secondaries from mesenchymatic cells. The paucity of chemical species does not allow clearcut histochemical results. Hyperactivity in previously trained muscle resulted in no significant changes. In untrained muscle vascular connective tissue and chemical changes were noted along with capillary increase in number and congestion, and phosphorylase and glycogen decrease. In denervated muscle, atrophy localizes in peripheral white fibers first; oxadative enzyme decrease; virtual complete loss of fat and glycogen occurs in these fibers; and loss of phosphorylase activity results. Intermediate and deep layers atrophy later. Severe myofibrillar alterations appear after 3rd week. Certain cells appear to be a weak regenerative attempt; however, no fibers appear. Degenerative phenomena appear more intense in red than in white fibers. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1967
- Accession Number
- AD0660284
Entities
People
- Maria Antonieta Rebollo
Organizations
- University of the Republic