PHOTOACTIVATION OF SMOOTH MUSCLE WITH THE RUBY LASER.

Abstract

Previous laser studies have indicated that a biologic effect is derived from the absorption of energy by a chromophore. Exceptions to this general rule, including the cessation of peristaltic movement in segments of chick intestine, have prompted a study of the response of smooth muscle systems to treatment with a ruby laser. Laser energy over a range of 100 to 1000 J/sq. cm was observed to stimulate contraction of smooth muscle from segments of salamander intestine and from excised rabbit iris sphincter muscle. The rapid contraction was observed to be confined to the tissue within the target diameter. Relaxation to its original state occurred within 1 to 4 minutes, depending upon the amplitude of the muscular excursion. Iris tissue containing pigment showed a response to a lower laser energy level, and the contractions showed a greater excursion than analogous tissue from an albino rabbit. The possibility of two-photon absorption by the nonpigmented muscle systems was discussed. (Author)

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1967
Accession Number
AD0660563

Entities

People

  • Donald E. Rounds
  • Robert S. Olson

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Absorption
  • Amplitude
  • Anatomy
  • Biological Sciences
  • Chromophores
  • Colorants
  • Energy Levels
  • Intestines
  • Lasers
  • Muscles
  • Ruby Lasers
  • Smooth Muscle
  • Tissues
  • Two Photon Absorption

Fields of Study

  • Medicine
  • Physics

Readers

  • Cardiovascular Physiology
  • Optical Physics and Photonics.
  • Vision Science/Vision Psychology/Cognitive Neuroscience.

Technology Areas

  • Directed Energy
  • Directed Energy - Lasers