The Role of Catecholamines and Serotonin in the Process of Adaptation to High Altitude

Abstract

The effects of hypoxia (12.85% O2 in N2) on the pulmonary artery pressure of dogs were studied, as well as the variations in the level of serotonin in the blood of the same artery. Hypoxia produced pulmonary hypertension in the 7 dogs studied, and at the same time an increase in the level of serotonin in the blood of the pulmonary artery was produced. This result is expounded in relation to a reflex vasoconstriction which is mediated by serotonin.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1967
Accession Number
AD0662631

Entities

People

  • Adriana Medina
  • G. Olaya
  • L. Utano

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Altitude
  • Arteries
  • Blood
  • Catecholamines
  • Catheters
  • High Altitude
  • Hypertension
  • Physiology
  • Pressure Transducers
  • Pulmonary Hypertension
  • Respiration
  • Respiratory Physiological Processes
  • Sea Level
  • Serotonin

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology