WHOLE BLOOD AMINO ACID CHANGES FOLLOWING RESPIRATORY-ACQUIRED PASTEURELLA TULARENSIS INFECTION IN MAN

Abstract

Significant changes in the whole blood amino acids of volunteers with respiratory-acquired Pasteurella tularensis (SCHU-S4) infection have been described. A decrease in whole blood amino acids occurred 12 to 60 hours after exposure and prior to the time that clinical symptomatology was apparent. The factors responsible for this decreased amino acid concentration were discussed but remain undefined. These changes were specifically related to infection, in that sham-exposed and similarly treated subjects did not manifest a similar response. The pattern of response was such that, in retrospect, it appeared to have predictive value for determining which subjects had been infected.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1967
Accession Number
AD0663853

Entities

People

  • Harry G. Dangerfield
  • Ralph D. Feigin

Tags

DTIC Thesaurus Topics

  • Acids
  • Albumins
  • Amino Acids
  • Animal Diseases
  • Anti-Bacterial Agents
  • Diseases And Disorders
  • Gammaproteobacteria
  • Glutamic Acid
  • Health Services
  • Infection
  • Infectious Diseases
  • Laboratory Procedures
  • Pain
  • Rodents
  • Signs And Symptoms
  • Therapy
  • Wound Infections

Fields of Study

  • Medicine
  • Psychology

Readers

  • Infectious Disease/Epidemiology
  • Molecular Genetics
  • Toxicology/Environmental Toxicology