INFLUENCE OF OXYGEN TOXICITY ON THE RATE OF RED CELL AGING

Abstract

The effect of oxygen toxicity on red cell aging was experimentally studied. The alterations in age distribution of red cells of rabbits submitted to a high oxygen concentration was determined by density distribution, osmotic fragility, acid fragility, and electron microscopy. Increased osmotic fragility and density of the red blood cells as well as an increased resistance to acid fragility is indicative of an increased population of structurally old cells. Red cell membranes as seen in the electron microscope present morphological features in agreement with this interpretation.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1967
Accession Number
AD0664339

Entities

People

  • David Danon

Organizations

  • Weizmann Institute of Science

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Age Distribution
  • Air
  • Air Force
  • Biomedical Research
  • Blood
  • Blood Cells
  • Cell Membrane
  • Cell Physiological Processes
  • Cells
  • Classification
  • Electron Microscopes
  • Electron Microscopy
  • Erythrocytes
  • Laboratory Animals
  • Materials
  • Rodents
  • Toxicity

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Materials Science and Engineering.

Technology Areas

  • Microelectronics