STUDIES ON LEPTOSPIROSIS IN THAILAND, WITH SPECIAL REFERENCE TO THE EPIDEMIOLOGY, PATHOLOGY AND CLINICAL ASPECTS, AND ITS RELATION TO ANIMAL RESERVOIR HOSTS.
Abstract
Epidemiological study of suspected cases of leptospirosis in 53 provincial hospitals in Thailand during September 1966 - August 1967 revealed 269 positives out of 1,927 cases (14%). Common serogroups were L. autumnalis, L. icterohemorragiae, L. bataviae, L. hebdomadis and L. australis. However, in Bangkok hospitals Leptospirosis bataviae was common. Clinical severity in 310 patients suffering from L. icterohemorrhagiae, L. bataviae and L. akiyami A were analysed, and those three serotypes were considered to be of high virulence from the standpoint of clinical manifestations and laboratory studies. The incidence of human leptospirosis from Quezon City, Manila, Philippines was studied and the results revealed positive residual antibodies of two per cent in 1966 and five per cent in 1967. At least six serogroups were involved in that area. Seventeen per cent of cases of pyrexia of unknown origin in Uttaradith provincial hospital of North Thailand were proved to be suffering from leptospirosis. L. bataviae was the most common serotype isolated from R. norvegicus obtained from eight municipalities of Central Thailand. L. canicola was the most common serogroup among dogs; L. javanica and L. akiyami A were the most common among field rats. In animal experiments, L. icterohemorrhagiae (Nakornsrithamraj), L. bataviae (Bangkok) and L. akiyami A (Pitsanuloke) were all proved to be of high virulence to hamsters. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1968
- Accession Number
- AD0665512
Entities
People
- Bundham Sundharagiati