PRESERVATION OF SUSCEPTIBILITY OF MAMMALIAN CELLS TO VIRAL INFECTION FOLLOWING STORAGE IN THE FROZEN STATE

Abstract

The research was concerned primarily with determining whether the susceptibility of mammalian cells to virus infection is altered by freezing and storage under liquid nitrogen. Although some investigations were made with so- called altered cell strains such as HeLa and KB, primary Rhesus monkey kidney cells were used as the biological system for most of this research. These primary cells were chosen because of their wide range of virus susceptibility, their relative ease of growth in vitro and the consistency of reproducibility of experimental results.

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Document Details

Document Type
Technical Report
Publication Date
Dec 15, 1967
Accession Number
AD0666015

Entities

People

  • R. W. Brown

Tags

Communities of Interest

  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Animal Structures
  • Cell Line
  • Cells
  • Electron Microscopy
  • Endoplasmic Reticulum
  • Freezing
  • Incubation
  • Infection
  • Monkeys
  • Nitrogen
  • Observation
  • Particles
  • Survival
  • Systems Biology
  • Virion
  • Viruses
  • Wound Infections

Readers

  • Computational Modeling and Simulation
  • Immunology