RADIATION INJURY OF MYELOPOIESIS IN MONKEYS,
Abstract
540-630 R OF GAMMA RADIATION COMPLETELY SUPPRESSED HEMOPOIESIS IN MONKEYS. During the first 8 days after exposure, leukocyte count in the peripheral blood dropped sharply, but the red blood cells showed no significant abnormalities. From the 9th to the 19th day, suppression of hemopoiesis became more pronounced. The leukocyte count dropped further and the concentration of hemoglobin decreased in the red blood cells. 30% of the animals died during this period but the first signs of recovery began to appear--occasional immature cell forms in the red marrow, and reticulocytes in the peripheral blood. During the third or restorative period (20th to 60th day) the animals appeared completely healthy, and the peripheral blood indices were more or less normal. It is suggested that these experiments may help to uncover the mechanisms underlying the development of leukemia and aplastic anemia caused by ionizing radiation. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 08, 1967
- Accession Number
- AD0666139
Entities
People
- M. I. Novikova
Organizations
- National Air and Space Intelligence Center