THE APPLICATION OF SELECTIVE ULTRAFILTRATION TO PROTEIN CHEMISTRY
Abstract
Preformed ultrafiltration membranes, with molecular weight exclusion limits varying from 1,000-100,000, are uniquely suited for preparative methods in protein chemistry. The applications include non-denaturing protein concentration, rapid dialysis, micro solute binding, limited purification, and fractionation of complex mixtures. In the latter procedures, selective ultrafiltration obviates the use of cumbersome electrophoretic methods, or initial column chromatography. Increases in the separation rate, as well as the total quantity of material fractionated, can be obtained by increasing the exchangeable surface of the filter.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 15, 1968
- Accession Number
- AD0666254
Entities
People
- William F. Blatt
Organizations
- United States Army Research Institute of Environmental Medicine