USE OF CHROMOSOME ABERRATIONS TO ESTIMATE X-RAY AND GAMMA-RAY DOSE TO MAN.
Abstract
The frequency of chromosome aberrations in lymphocytes taken from the peripheral blood provides a useful measure of absorbed dose. The estimation of dose is affected by time in culture of the lymphocytes, by sampling error and sampling time, and by size, rate, distribution, and quality of radiation dose. Data on the effect of these variables are presented. Dose is estimated for five people accidentally exposed to ionizing radiation. Four appendixes give a detailed account of optimal technics for making chromosome preparations, the yields of aberrations as a function of dose in 50-hour and 72-hour cultures, and the yield of acentric fragments per dicentric. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1967
- Accession Number
- AD0666713
Entities
People
- Amos Norman
- Masao S. Sasaki
- Richard E. Ottoman
- Robert C. Veomett
Organizations
- UCLA David Geffen School of Medicine