THYROID STATUS OF DOGS CONTINUOUSLY EXPOSED TO ONE-HALF ATMOSPHERE

Abstract

Six male beagle dogs were maintained on ambient air at one-half atmosphere for 33 days and were monitored for protein-bound iodine (PBI), thyroid I 131 avidity, plasma triiodothyronine uptake, and plasma 17-hydroxycorticosteroids. Data were compared with those from littermate controls held at ground level. Increased I 131 uptake and reduced triiodothyronine uptake were observed in the altitude-exposed dogs, while no change in the peripheral blood hydrocortisone level was seen. No difference in the gross, microscopic, or ultrastructural anatomy of the thyroid glands of groups was noted.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1967
Accession Number
AD0666906

Entities

People

  • David H. Wood

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical
  • Space

DTIC Thesaurus Topics

  • Anatomy
  • Blood
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Endocrine Glands
  • Environment
  • Glands
  • Ground Level
  • Hormones
  • Laboratory Animals
  • Medical Personnel
  • Proteins
  • Thyroid Glands
  • Thyroid Hormones
  • Thyroxine
  • Veins

Readers

  • Cardiovascular Physiology
  • Toxicology/Environmental Toxicology