DEXAMETHASONE-INDUCED PITUITARY-ADRENAL SUPPRESSION AS MEASURED BY PAROTID FLUID STEROID LEVELS.
Abstract
Dexamethasone-21-phosphate (2 mg.) administered to healthy volunteers as a retention enema at 8:00 a.m. produced significant depression of serum and parotid fluid free 17-hydroxycorticosteroids by 3:00 p.m. Measurements of parotid fluid free 17-OHCS may be used to detect changes in adrenocortical function. Pituitary-adrenal suppression may occur after the use of intrarectal soluble adrenal corticosteroids. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1967
- Accession Number
- AD0666924
Entities
People
- Ira L. Shannon
- Marshall Sparberg
- Robert L. Jenson
- Steven C. Beering
Organizations
- United States Air Force School of Aerospace Medicine