Serum Enzyme Changes After Physical Exertion

Abstract

A study of alterations in selected serum enzymes after physical exertion by young males is reported. Mean serum concentrations of glutamic oxalacetic transaminase (SGOT), lactate dehydrogenase and amylase all increase after the performance of vigorous exercise. SGOT concentrations in the abnormal range are often reached both immediately after exertion to near exhaustion and on the day following vigorous performance of calisthenics. These evaluations appear to represent two distinct SGOT peaks. Increments in SGOT concentrations found immediately after exercise correlate highly with alterations in blood lactate, blood pyruvate and blood pH, but not with changes in serum potassium. Thus, the initial peak is associated in some unknown manner with anaerobic glycolysis. The second SGOT peak is probably related to the destruction of skeletal muscle. Low resting SGOT concentrations correlate significantly with better performances in physical fitness tests. Also, the later SGOT rise is abolished by a 10-week period of physical conditioning. Thus, the measurement of serum enzyme concentrations appears to be potentially useful in the assessment of physical fitness.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1968
Accession Number
AD0667471

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  • I. D. Wilson

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  • Blood
  • Chemistry
  • Heart Rate
  • Marine Corps
  • Measurement
  • Muscles
  • Myocardial Ischemia
  • Navy
  • New York
  • North Carolina
  • Pain
  • Physical Examination (Medicine)
  • Physical Fitness
  • Physiology
  • Skeletal Muscle
  • Test And Evaluation
  • United States

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  • Analytical Chemistry
  • Cardiovascular Physiology
  • Exercise and Sports Science.