FLUOROMETRIC DETECTION OF BIOLOGICAL CHANGES IN IRRADIATED LABORATORY ANIMALS.

Abstract

The exposure of rats to either 80 or 230 rad of gamma irradiation from a Cobalt-60 source was found to effect the levels of certain fluorescent fractions excreted in urine. In addition to the changes in fluorometrically detectable fractions, an ultraviolet absorbing component, in urine, was found to increase following 80 rad of whole body irradiation. The effects of radiation on body weights, creatinine and urine excretion were observed only at the 230 rad dose. Fluorometric, spectrophotometric, fractionation techniques of urine samples are described. (Author)

Document Details

Document Type
Technical Report
Publication Date
Oct 31, 1966
Accession Number
AD0667566

Entities

People

  • J. A. Demetriou

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Animals
  • Biological Sciences
  • Body Weight
  • Creatinine
  • Detection
  • Excretion
  • Fractionation
  • Laboratory Animals
  • Radiation
  • Urine
  • Whole Body Irradiation

Fields of Study

  • Medicine
  • Physics

Readers

  • Cardiovascular Physiology
  • Molecular and Cellular Biochemistry
  • Spectroscopy.