EFFECT OF SODIUM FLUORIDE AND AMOX (NF3O) ON GROWTH AND THYROID FUNCTION IN THE RAT

Abstract

Intact and thyroidectomized growing rats were treated daily for 60 days with thyroxine, potassium iodide, sodium fluoride, or NF3O, an oxidizing substance. Results indicated that treatment with NaF or NF3O at doses which were molar equivalents with respect to fluoride to a thyrotoxic dose of iodide had no effect on thyroid function measured by growth rate, 131 I-uptake, and adrenal weight. A sparing effect of thyroid on NF3O toxicity was suggested.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1968
Accession Number
AD0671942

Entities

People

  • Ethard W. Van Stee

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Biomedical Research
  • Body Weight
  • Chemistry
  • Classification
  • Endocrine Glands
  • Fluorides
  • Fluorine
  • Fluorine Compounds
  • Governments
  • Potassium
  • Potassium Iodide
  • Security
  • Thyroid Glands
  • Thyroxine
  • Toxicity

Readers

  • Cardiovascular Physiology
  • Combustion science or combustion engineering.
  • Toxicology/Environmental Toxicology