EFFECTIVENESS OF DRUGS IN ANIMALS EXPOSED TO MIXED GAMMA-NEUTRON RADIATIONS. III. PSYCHOPHARMACOLOGIC AGENTS,

Abstract

Chlorpromazine, triflupromazine, and chlordiazepoxide were studied for their effectiveness in irradiated male Sprague-Dawley rats at selected times following 500-, 1000-, and 10,000-rad whole body doses of mixed gamma-neutron radiations. A conditioned response was used to test the drugs' effectiveness. Drug effectiveness decreased in the rats receiving 1000 rads and increased in those receiving 10,000 rads when compared to unirradiated controls. (Author)

Document Details

• Document Type: Technical Report
• Publication Date: May 01, 1968
• Accession Number: AD0672741

Entities

People

• L. W. Davis
• T. A. Strike

Organizations

• Armed Forces Radiobiology Research Institute

Tags

DTIC Thesaurus Topics

• Chemical Compounds
• Chlorpromazine
• Cyclic Compounds
• Heterocyclic Compounds
• Organic Compounds
• Radiation

Fields of Study

• Psychology

Readers

• Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.
• Nuclear and Radiation Engineering.
• Toxicology/Environmental Toxicology