Histoplasmosis
Abstract
Histoplasmosis (Synonyms: Darling's disease, Darling's cytomycosis Reticuloendothelial cytomycosis) is a fungus disease of man and animals in the nature of a parasitic reticuloendotheliosis. The yeast like forms of H capsulatum are rounded bodies, 1 - 4 microns in diameter, containing a polymorphochromatin nucleus, basophil protoplasm and a capsule. The parasite develops and multiplies in the reticuloendothelial cells in the organs of humans and animal organisms. A reservoir for the infection are animals chronically suffering with this disease. Infection may originate by an aerial, cutaneous path or through the digestive tract. Hyperplasia of reticuloendothelial elements, in whose protoplasm parasites are observed, is observed microscopically in the organs and tissues. It is characterized by the absence of signs of suppurative inflammation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0673206
Entities
People
- E. Berezina
Organizations
- United States Army Biological Warfare Laboratories