EARLY HEMATOLOGIC CHANGES IN THE RHESUS MONKEY AFTER SUPERLETHAL MIXED NEUTRON-GAMMA IRRADIATION

Abstract

To determine early hematologic response to mixed neutron-gamma irradiation, twenty Macaca mulatta monkeys were exposed to pulsed doses of 2, 500, 3,750, and 5,000 rads. Hematologic data at 4 hours postirradiation indicated a marked leukocytosis in all groups. The cellular increase was due to the increase of neutrophils contrasted to the lymphocytes, which decreased to less than half their baseline value. There was also a thrombocytosis at 4 hours postirradiation. Serum enzyme concentrations were determined with observed increases of lactic dehydrogenase and glutamic oxalacetic transaminase; however, the response was highly variable.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1968
Accession Number
AD0673352

Entities

People

  • Donald R. Anderson
  • Robert J Young

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Air Force
  • Air Force Facilities
  • Analysis Of Variance
  • Animals
  • Blood
  • Blood Counts
  • Blood Proteins
  • Cells
  • Chemistry
  • Granulocytes
  • Hematologic Diseases
  • Ionizing Radiation
  • Proteins
  • Radiation
  • Statistical Analysis
  • X Rays

Readers

  • Cardiovascular Physiology
  • Immunology
  • Nuclear and Radiation Engineering.