A STUDY OF THE IMMUNOLOGIC ASPECTS OF THERAPY OF RADIATION INJURY IN THE SOLDIER.

Abstract

The study was conducted as a part of a broad review of selected problems in military medicine-research and development, to provide the Office of The Surgeon General of the Army with the most current information on the treatment of ionizing radiation injury in the soldier. These studies and their comprehensive, evaluative bibliographies will facilitate the evaluation of future research and development programs on the treatment of radiation injury and military nuclear medicine. The report includes the nature of hematopoietic injury and recovery, immunologic changes that influence bone marrow allograft transplants and the decreased resistance to infection, animal models used to study allograft responses, use of antilymphocyte sera and antilymphocyte globulin as immunosuppressive substances, and the phenomena of host-versus-graft and graft-versus-host reactions. The evidence for the reported success with leukocyte typing for donor selection is reviewed as related to bone marrow transplantation. An annotated, evaluative bibliography is included as an appendix. (Author)

Document Details

Document Type
Technical Report
Publication Date
May 15, 1968
Accession Number
AD0674262

Entities

People

  • C. Jelleff Carr

Organizations

  • Federation of American Societies for Experimental Biology

Tags

DTIC Thesaurus Topics

  • Allografts
  • Bibliographies
  • Bone Marrow
  • Bones
  • Infection
  • Ionizing Radiation
  • Military Medicine
  • Nuclear Medicine
  • Radiation
  • Radiation Injuries
  • Transplants
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Immunology
  • Library and Information Science
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology