OBTAINANCE OF ANTHRAX STRAINS FOR THE PURPOSE OF PROPHYLACTIC VACCINATION (POLUCHENIO SIRBIROYAZVENNYKH SHTAMMOV DLLA TSELEI VAKTSINOPROFILAKTIKI)
Abstract
The anthrax vaccine obtained by 'directed effectuation' and selection proved to be harmless and immunogenic, when tested on rabbits. The same vaccine, tested for harmlessness on sheep and goats in the conditions of the Institute, showed that it is harmless and stimulates just a minor local and thermal reaction. It was determined that the vaccine produces stable immunity at a control after 15 days and after 4 months subsequent inoculation; this was proved by testing the vaccines for stability and length of the immunity period on sheep. Further studies of the vaccine should be conducted in testing its harmlessness and effectiveness on agricultural animals at large and in rigorous experiments for the length and stability of its produced immunity.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1968
- Accession Number
- AD0674926
Entities
People
- S. G. Kolosov
- Yu. F. Borisovich
Organizations
- United States Army Biological Warfare Laboratories