CIRCADIAN CYCLES OF LACTIC DEHYDROGENASE IN URINE AND BLOOD PLASMA: RESPONSE TO HIGH PRESSURE

Abstract

The existence of circadian cycles of plasma lactic dehydrogenase has been confirmed. This cycle is characterized by having its lowest activity at 0800 hours and its highest activity between 1600-2000 hours. A diurnal variation in urinary excretion of lactic dehydrogenase has been described which features an inverse relationship to that of the plasma in that maximum excretion occurs during the 0800-1200 hour period while minimum excretion is present between 1600-2400 hours. High pressure stress applied to the ascending phase of the plasma cycle causes no abnormal response while the same treatment applied to the descending segment elicits a second peak of lactic dehydrogenase activity. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jun 14, 1968
Accession Number
AD0675070

Entities

People

  • Karl E. Schaefer
  • Michael J. Jacey

Organizations

  • Naval Submarine Medical Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acid-Base Imbalance
  • Aerospace Medicine
  • Base Lines
  • Biomedical Research
  • Blood
  • Blood Plasma
  • Cell Membrane
  • Cell Membrane Permeability
  • Cellular Structures
  • Clinical Laboratories
  • Compressed Air
  • Diurnal Variations
  • Excretion
  • High Pressure
  • Measurement
  • Medical Personnel
  • Navy

Readers

  • Cardiovascular Physiology
  • Space/Atmospheric Physics.