IMMUNOGENIC AND ANTIGENIC ACTIVITY OF INACTIVATED TISSUE-CULTURE VACCINE FOR VIRUSES OF THE TICK-BORNE ENCEPHALITIS COMPLEX

Abstract

The existence of various viruses in the tick-borne encephalitis complex established the necessity for studying the effectiveness of a vaccine against one of the viruses in respect to the remaining representatives of the complex. Serological investigations of human sera are limited to the identification of antibodies to the virus in persons inoculated with vaccine against tick-borne encephalitis, and also antibodies to the viruses of tick- borne encephalitis and Langat after immunization with live Langat virus. Considering the absence of systematic investigations in this direction, the immunogenic and antigenic properties of tissue-culture vaccine were studied in respect to all the presently known viruses of the tick-borne encephalitis antigen complex.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1968
Accession Number
AD0675103

Entities

People

  • D. K. Lvov
  • L. S. Levina
  • M. P. Chumakov
  • V. A. Zaklinskaya

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Animals
  • Antibodies
  • Arbovirus Infections
  • Blood
  • Diseases And Disorders
  • Encephalitis
  • Flavivirus Infections
  • Frequency
  • Immunization
  • Infection
  • Nervous System
  • Resistance
  • Ticks
  • Tissue Culture
  • Vaccination
  • Viral Hemorrhagic Fevers
  • Viruses

Fields of Study

  • Biology
  • Medicine

Readers

  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology