NEUTRALIZATION REACTION OF THE VENEZUELAN ENCEPHALOMYELITIS VIRUS BASED ON THE HEMAGGLUTINATION PHENOMENON,
Abstract
The neutralization reaction of the Venezuelan equine encephalomyelitis virus in tissue cultures, based on the phenomenon of hemagglutination, makes it possible to obtain results in 18 hours instead of the 72 hours required for an evaluation based on the cytopathological effect. When investigating the sera of convalescents in the neutralization reaction in tissue cultures, practically the same results are obtained during evaluation by both methods. The immune sera of rabbits gave significantly higher neutralization indices when evaluated according to hemagglutination. Complement-fixing antibodies in titers of 1:8--1:16 were still detected in the sera of convalescents 8 years following illness. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1966
- Accession Number
- AD0675113
Entities
People
- S. Ya. Gaidamovich
- V. A. Vagzhanova
Organizations
- United States Army Biological Warfare Laboratories